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	Provedor de dados BJMBR (1) Autor Heldin,P. (1) Palavra-chave Extracellular matrix (1) Hyaluronan (1) Hyaluronidase (1) Pericellular matrix (1) Synthase (1) Tumor invasion (1) Mais... Tipo do documento Info:eu-repo/semantics/article (1) Ano 2003 (1) País Brazil (1) Idioma Inglês (1)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 1 Primeira ... 1 ... Última Importance of hyaluronan biosynthesis and degradation in cell differentiation and tumor formation BJMBR Heldin,P.. Hyaluronan is an important connective tissue glycosaminoglycan. Elevated hyaluronan biosynthesis is a common feature during tissue remodeling under both physiological and pathological conditions. Through its interactions with hyaladherins, hyaluronan affects several cellular functions such as cell migration and differentiation. The activities of hyaluronan-synthesizing and -degrading enzymes have been shown to be regulated in response to growth factors. During tumor progression hyaluronan stimulates tumor cell growth and invasiveness. Thus, elucidation of the molecular mechanisms which regulate the activities of hyaluronan-synthesizing and -degrading enzymes during tumor progression is highly desired. Tipo: Info:eu-repo/semantics/article Palavras-chave: Hyaluronan; Synthase; Hyaluronidase; Tumor invasion; Extracellular matrix; Pericellular matrix. Ano: 2003 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2003000800002 Registros recuperados: 1 Primeira ... 1 ... Última

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